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This required course for undergraduate bioinformatics majors provides foundational knowledge on database aspects used in the field and an overview of their applications in bioinformatics, biomedical informatics, and health/clinical informatics. The course begins with a brief review of key concepts in computational molecular biology related to database search/development, database management systems, the difference between primary and secondary databases, and bioinformatics-related aspects of modeling and theory in computer science. The major focus is on the multiple challenges and aspects of bio-database development, search, and pattern discovery. The course uses problem-based learning to help students develop database management skills as they apply to high throughput "-omics." data, the basics of data management, data provenance and governance, standards, and analysis through KDD-based workflows. This course will also consider the fundamentals of artificial intelligence and machine learning as they pertain to bioinformatics, from the perspective of database storage, I/O, and analysis. (Cross-listed with BIOI 4870)

Prerequisite(s): CSCI 3320 and BIOI 3500, or permission of instructor; BIOI 3500 can be taken concurrently. Prior completion of CSCI 4850 is strongly recommended but not required. Not open to non-degree graduate students.